If you’ve been prescribed Mounjaro (tirzepatide), you may be wondering: does Mounjaro need to be refrigerated? Proper storage is essential to ensure the medication remains safe and effective, especially if you’re new to injectable weight-loss treatments.
At RX Direct, our pharmacy team regularly supports patients using Mounjaro and Wegovy. Below, we explain exactly how to store Mounjaro, what to do if it’s been left out, and how to use it safely. If you’re looking for further support, don’t hesitate to book with our friendly team today.
Does Mounjaro Need to Be Refrigerated?
Yes, Mounjaro should be refrigerated before first use.
Unopened Mounjaro pens should be stored in a refrigerator at 2°C to 8°C. This helps maintain the stability and effectiveness of the medication.
However, there is some flexibility once the pen is in use.
Can Mounjaro Be Kept Out of the Fridge?
Yes. After removing Mounjaro from the fridge, it can be kept at room temperature (below 30°C) for a limited time.
Storage rules at a glance:
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Unopened pen:
Store in the fridge (2°C–8°C) -
Once removed from fridge:
Can be kept at room temperature for up to 30 days -
Do not freeze
If Mounjaro has been frozen, it must not be used -
Keep away from heat and sunlight
What Happens If Mounjaro Isn’t Refrigerated?
If Mounjaro is stored incorrectly, the medication may become less effective or unsafe to use. Improper storage can cause:
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Reduced appetite suppression
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Inconsistent weight-loss results
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Risk of medication breakdown
If you’re unsure whether your pen is still safe, it’s best to contact your pharmacy or prescriber before injecting.
RX Direct’s team can advise whether your medication should be replaced.

Travelling With Mounjaro
Many patients worry about storing Mounjaro while travelling, especially during warmer months.
Helpful travel tips:
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Use an insulated medication travel case
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Avoid placing pens directly on ice packs
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Keep medication out of direct sunlight
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Do not store in checked luggage if flying
Because Mounjaro can remain at room temperature for up to 30 days, short trips are usually manageable without refrigeration — provided temperatures stay below 30°C.
Does Mounjaro Need To Be Refrigerated After First Use?
Once a pen has been taken out of the fridge, it does not need to be returned, but it can be if you prefer.
What matters most is that:
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The total time outside refrigeration does not exceed 30 days
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The pen is not exposed to heat or freezing temperatures
Consistency and safe storage are key.
Mounjaro Storage FAQs
Can I put Mounjaro back in the fridge after it’s been out?
Yes. As long as it has been stored correctly and hasn’t exceeded the 30-day room-temperature limit.
What if Mounjaro arrives warm in the post?
RX Direct uses appropriate packaging to protect temperature during delivery. If your medication feels warm or you’re concerned, contact the pharmacy before using it.
Can I store Mounjaro in the bathroom?
No. Bathrooms are often humid and subject to temperature changes, which can affect medication stability.
How do I know if Mounjaro has gone bad?
Do not use the pen if the solution appears cloudy, discoloured, or contains particles. When in doubt, seek professional advice.
Why Proper Storage Protects Your Results
Correct storage isn’t just about safety, it directly affects how well Mounjaro works. Temperature fluctuations can impact the stability of tirzepatide, potentially reducing its appetite-suppressing effects over time. By storing Mounjaro correctly, you help ensure each weekly dose delivers consistent results and supports steady progress.
If you’re ever unsure about how your medication has been stored, it’s always better to check before injecting. Our team can advise whether your pen is still safe to use or if a replacement is needed.
Remember, following proper storage advice is just as important as taking the injection at the correct time.

Support From RX Direct
At RX Direct, we don’t just supply medication, we provide ongoing support and guidance throughout your weight loss journey.
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Secure online consultations
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Licensed UK prescribers
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Clear storage and usage advice
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Discreet home delivery
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Ongoing support if issues arise
Whether you’re starting Mounjaro or switching from Wegovy, our team is here to help.
So, Does Mounjaro Need To Be Refrigerated?
Yes, before use, it should be kept in the fridge. After removal, it can stay at room temperature for up to 30 days, provided it’s stored safely and kept below 30°C.
If you’re ever unsure about storage, side effects, or dosing, seeking professional advice is always the safest option.
Need personalised guidance on Mounjaro storage?
Book an online consultation with RX Direct today and get expert support from our Middlesbrough pharmacy team.

